Current lab members
I finished my Master's degree in Cardiff University where I worked in the lab of Prof. Helen White-Cooper, using imaging approaches and mathematical analysis to investigate the transport of a unique set of intracellular proteins in Drosopila spermatids. Currently, I'm a final year PhD student looking at the mechanical events of actin-mediated particle uptake by immune cells called phagocytosis. I use different types of live imaging, super-resolution and electron microscopy techniques to capture phagocytic events in in vitro setting. My experimental data are compared with simulations by working very closely with theoretical physicists to better understand the biophysical underpinnings of phagocytic process.
Outside the lab, I enjoy singing with my choir, travelling and exploring the beautiful sceneries of the UK and Europe.
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I completed Masters in Pharmacology at the University of Bath in 2017. Here, I found a passion for studying respiratory disease, further solidified by a year-long industrial placement at GSK in the respiratory department.
Now I am a third year DiMeN DTP (MRC) PhD student, who is attempting to understand how the healthy immune system is able to clear Cryptococcus neoformans in the lung. To do this, I use mouse models and ex vivo precision cut lung slices to directly visualise host-pathogen interactions in mammalian tissue.
In my spare time, I maintain a live music review blog, take part in tough mudders and am currently designing combat robots.
I'm a 3rd year PhD researcher, having joined the lab in 2017 after completing BSc Pharmacology and MSc Translational Neuroscience . My research, funded under an MRC DiMeN DTP studentship, is focused on developing therapies for cryptococcal meningitis. For this, I have developed and optimised zebrafish models for high-throughput drug screening. In addition, I have been researching how antifungals get in to the central nervous system, and how this can be modulated for improved disease outcomes.
When I'm not in the lab, I'm usually busy with my many, many plants, trying to build something or working on disability equality in academia.
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I finished my undergraduate degree at the University of Aberdeen with a BSc (Hons) in Microbiology in 2017.
Currently I am a third year PhD student supervised by Professor Kathryn Ayscough (BMS) and Dr Simon Johnston. My studentship is funded by BBSRC DTP White Rose. I work on elucidating the role of cell wall composition and hyphal switch during the host-pathogen interactions of a commensal fungal pathogen called Candida albicans.
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In 2018 I completed a Master’s degree in Translational neuroscience. During my masters project I was supervised by Prof. Marysia Placzek. I contributed to her work in understanding the genetics of early hypothalamic development in the chick embryo animal model. During my master's degree I found a passion for incorporating different scientific disciplines to understand neurological pathologies, which lead me to my choice of an interdisciplinary project for my PhD.
My PhD project works on the understanding of the mechanisms of raised intracranial pressure in cryptococcal meningitis. My focus is the pathophysiological processes arising from the biophysical properties of the pathogen. It appears that cryptococcal infections affects intracranial pressure in a very complex way, involving all the components of the cranium: brain, vasculature and CSF circulation. My project involves using a zebrafish infection model to mimic the mechanisms that cause this increase in pressure.
I studied my undergrad in biotechnology engineering at the National Polytechnic Institute in Mexico. After that I applied for a direct PhD at the IICD department of the Medical School. My work is focused on DNA replication inhibitor as potential antimicrobial agents against parasitic (Trypanosoma brucei and Leishmania infantum) and fungal organisms (Cryptococcus neoformans).
I really love my country and my culture and I will constantly speak about (specially food, which sometimes I cook if you want to give it a try).
I joined the lab in 2019, as part of the DiMeN DTP. Having completed a MSc in Clinical microbiology and having worked in Dr Catherine Pashley’s Clinical mycology lab, I developed a strong interest in opportunistic infections in respiratory disorders. My project - in collaboration with AstraZeneca – aims to observe the effects of the IL-33/ST2 pathway in chronic respiratory diseases and infections. We will use an inter-disciplinary approach to explore this field.
Throughout this PhD I also hope to promote inclusivity within academia and STEM by representing women and the black and minority ethnic (BAME) community.
Previous lab members
Dr. James Bradford